Creating tissue on chip constructs in microtitre plates for drug discovery

Article English OPEN
Reboud, J.; Macdonald, N.P.; Menachery, A.; Cooper, J.M.;
(2018)
  • Publisher: Royal Society of Chemistry

We report upon a novel coplanar dielectrophoresis (DEP) based cell patterning system for generating transferrable hepatic cell constructs, resembling a liver-lobule, in culture. The use of paper reinforced gel substrates provided sufficient strength to enable these cons... View more
  • References (50)
    50 references, page 1 of 5

    1 J. W. Allen and S. N. Bhatia, Tissue Eng., 2002, 8, 725-737.

    2 A. S. Rudolph and J. Reasor, Biosens. Bioelectron., 2001, 16, 429-431.

    3 W. M. Saltzman and W. L. Olbricht, Nat. Rev. Drug Discovery, 2002, 1, 177-186.

    4 R. Singhvi, G. Stephanopoulos and D. I. Wang, Biotechnol. Bioeng., 1994, 43, 764-771.

    5 M.-Y. Chiang, Y.-W. Hsu, H.-Y. Hsieh, S.-Y. Chen and S.-K. Fan, Sci. Adv., 2016, 2, e1600964.

    6 L. G. Griffith and M. A. Swartz, Nat. Rev. Mol. Cell Biol., 2006, 7, 211-224.

    7 L. A. Low and D. A. Tagle, Lab Chip, 2017, 17, 3026-3036.

    8 A. D. v. d. Meer and A. v. d. Berg, Integr. Biol., 2012, 4, 461- 470.

    9 S. N. Bhatia and D. E. Ingber, Nat. Biotechnol., 2014, 32, 760- 772.

    10 M. Baker, Nature, 2011, 471, 661-665.

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