Three-dimensional computational model of a blood oxygenator reconstructed from micro-CT scans

Article English OPEN
D'Onofrio, C.; van Loon, R.; Rolland, S.; Johnston, R.; North, L.; Brown, S.; Phillips, R.; Sienz, J.;
  • Publisher: Elsevier

Cardiopulmonary bypass procedures are one of the most common operations and blood oxygenators are the centre piece for the heart-lung machines. Blood oxygenators have been tested as entire devices but intricate details on the flow field inside the oxygenators remain unk... View more
  • References (25)
    25 references, page 1 of 3

    [1] ANSYS Inc. ®, Ansys academic research - fluent. Simulation-Driven Product Development. URL http://www.ansys.com/. 2013.

    [2] Berggren SM. The oxygen deficit of arterial blood caused by non-ventilating parts of the lung. Johnson Repr. Corporation; 1964.

    [3] Bhavsar SS, Schmitz-Rode T, Steinseifer U. Numerical modeling of anisotropic fiber bundle behavior in oxygenators. Artif Organs 2011;35(11):1095-102. doi:10.1111/j.1525-1594.2011.01365.x.

    [4] Chatburn RL, Volsko TA, Hazy J, Harris LN, Sanders S. Determining the basis for a taxonomy of mechanical ventilation. Respir Care 2012;57(4):514-24. doi:10. 4187/respcare.01327.

    [5] Consolo F, Fiore GB, Pelosi A, Reggiani S, Redaelli A. A numerical performance assessment of a commercial cardiopulmonary by-pass blood heat exchanger. Med. Eng. Phys. 2015;37(6):584-92. http://dx.doi.org/10.1016/j.medengphy. 2015.03.002.

    [6] Gartner MJ, Wilhelm CR, Gage KL, Fabrizio MC, Wagner WR. Modeling flow effects on thrombotic deposition in a membrane oxygenator. Artif Organs 2000;24(1):29-36. doi:10.1046/j.1525-1594.2000.06384.x.

    [7] GOV.UK, Medicines & healthcare products regulatory agency UK, Online, page visited 2016-09, 2016, https://www.gov.uk/government/organisations/ medicines-and-healthcare-products-regulatory-agency.

    [8] Haworth WS. The development of the modern oxygenator. Ann Thoracic Surg 2003;76(6):S2216-19. doi:10.1016/j.athoracsur.2003.09.012.

    [9] Hormes M, Borchardt R, Mager I, Rode TS, Behr M, Steinseifer U. A validated cfd model to predict O2 and CO2 transfer within hollow fiber membrane oxygenators. Int J Artif Organs 2011;34(3):317-25. http://europepmc.org/abstract/ MED/21462147

    [10] HSE. Health and safety executive. Chronic obstructive pulmonary disease (copd)2015. Online. http://www.hse.gov.uk/statistics/causdis/copd/.

  • Related Organizations (4)
  • Metrics
Share - Bookmark