Pseudotyped αvβ6 integrin-targeted adenovirus vectors for ovarian cancer therapies

Article English OPEN
Uusi-Kerttula, Hanni; Davies, James; Curtis, Sarah; Chester, John; Parker, Alan;
(2016)
  • Publisher: Impact Journals
  • Identifiers: doi: 10.18632/oncotarget.8545
  • Subject: R1
    mesheuropmc: biochemical phenomena, metabolism, and nutrition | viruses | hemic and lymphatic diseases

Encouraging results from recent clinical trials are revitalizing the field of oncolytic virotherapies. Human adenovirus type 5 (HAdV-C5/Ad5) is a common vector for its ease of manipulation, high production titers and capacity to transduce multiple cell types. However, e... View more
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