publication . Article . Other literature type . 2017

The effects of improving sleep on mental health (OASIS): a randomised controlled trial with mediation analysis

Freeman, Daniel; Sheaves, Bryony; Goodwin, Guy M; Yu, Ly-Mee; Nickless, Alecia; Harrison, Paul J; Emsley, Richard; Luik, Annemarie I; Foster, Russell G; Wadekar, Vanashree; ...
Open Access English
  • Published: 01 Oct 2017
  • Publisher: Elsevier
Abstract
Sleep difficulties might be a contributory causal factor in the occurrence of mental health problems. If this is true, improving sleep should benefit psychological health. We aimed to determine whether treating insomnia leads to a reduction in paranoia and hallucinations. We did this single-blind, randomised controlled trial (OASIS) at 26 UK universities. University students with insomnia were randomly assigned (1:1) with simple randomisation to receive digital cognitive behavioural therapy (CBT) for insomnia or usual care, and the research team were masked to the treatment. Online assessments took place at weeks 0, 3, 10 (end of therapy), and 22. The primary ou...
Subjects
free text keywords: A300 Clinical Medicine, C841 Health Psychology, C860 Neuropsychology, /dk/atira/pure/researchoutput/pubmedpublicationtype/D016428, Journal Article, /dk/atira/pure/subjectarea/asjc/2700/2738, Psychiatry and Mental health, /dk/atira/pure/subjectarea/asjc/2800/2803, Biological Psychiatry, C800, RC0321, Articles, BF, Clinical psychology, Psychiatry, medicine.medical_specialty, medicine, Psychological intervention, Cognitive therapy, medicine.medical_treatment, Cognitive behavioral therapy, Mental health, Insomnia, medicine.symptom, business.industry, business, Randomized controlled trial, law.invention, law, Paranoia, Population, education.field_of_study, education
Related Organizations
Funded by
WT| Sleep and Circadian Neuroscience Institute (SCNi)
Project
  • Funder: Wellcome Trust (WT)
  • Project Code: 098461
  • Funding stream: Neuroscience and Mental Health
37 references, page 1 of 3

1 Harvey AG, Murray G, Chandler R, Soehner A. Sleep disturbance as transdiagnostic: consideration of neurobiological mechanisms. Clin Psychol Rev 2011; 31: 225-35.

2 Freeman D, Pugh K, Vorontsova N, Southgate L. Insomnia and paranoia. Schizophr Res 2009; 108: 280-84.

3 Reeve S, Sheaves B, Freeman D. The role of sleep dysfunction in the occurrence of delusions and hallucinations. Clin Psychol Rev 2015; 42: 96-115. [OpenAIRE]

4 Kendler KS, Campbell J. Interventionist causal models in psychiatry: repositioning the mind-body problem. Psychol Med 2009; 39: 881-87.

5 Dunn G, Emsley R, Liu H, et al. Evaluation and validation of social and psychological markers in randomised trials of complex interventions in mental health: a methodological research programme. Health Technol Assess 2015; 19: 1-115.

6 Emsley R, Dunn G, White IR. Mediation and moderation of treatment efects in randomised controlled trials of complex interventions. Stat Methods Med Res 2010; 19: 237-70.

7 Taylor M, Gregory A, Freeman D, Ronald A. Do sleep disturbances and psychotic experiences in adolescence share genetic and environmental influences? J Abnorm Psychol 2015; 124: 674-84.

8 Sheaves B, Porcheret K, Tsanas A, et al. Insomnia, nightmares and chronotype as markers of risk for severe mental illness. Sleep 2016; 39: 173-81.

9 Qaseem A, Kansagara D, Forciea M, Cooke M, Denberg T. Management of chronic insomnia disorder in adults: a clinical practice guideline from the American College of Physicians. Ann Intern Med 2016; 165: 125-33. [OpenAIRE]

10 Ritterband L, Thorndike F, Ingersoll K, et al. Efect of a web-based cognitive behaviour therapy for insomnia intervention with a 1-year follow-up: a randomized clinical trial. JAMA Psychiatry 2017; 74: 68-75. [OpenAIRE]

11 Espie C, Kyle S, Williams C, et al. A randomized, placebo-controlled trial of online cognitive behavioral therapy for chronic insomnia disorder delivered via an automated media-rich web application. Sleep 2012; 35: 769-81. [OpenAIRE]

12 Christensen H, Batterham P, Gosling J, et al. Efectiveness of an online insomnia program (SHUTi) for prevention of depressive episodes (the GoodNight Study): a randomised controlled trial. Lancet Psychiatry 2016; 3: 333-41.

13 Freeman D, Waite F, Startup H, et al. Eficacy of cognitive behavioural therapy for sleep improvement in patients with persistent delusions and hallucinations (BEST): a prospective, assessor-blind, randomised controlled pilot study. Lancet Psychiatry 2015; 2: 975-83.

14 Bilderbeck A, Atkinson L, McMahon H, et al. Psychoeducation and online mood tracking for patients with bipolar disorder. J Afect Disord 2016; 205: 245-51. [OpenAIRE]

15 Freeman D, Sheaves B, Goodwin G, et al. Efects of cognitive behavioural therapy for insomnia on the mental health of university students. Trials 2015; 16: 236.

37 references, page 1 of 3
Abstract
Sleep difficulties might be a contributory causal factor in the occurrence of mental health problems. If this is true, improving sleep should benefit psychological health. We aimed to determine whether treating insomnia leads to a reduction in paranoia and hallucinations. We did this single-blind, randomised controlled trial (OASIS) at 26 UK universities. University students with insomnia were randomly assigned (1:1) with simple randomisation to receive digital cognitive behavioural therapy (CBT) for insomnia or usual care, and the research team were masked to the treatment. Online assessments took place at weeks 0, 3, 10 (end of therapy), and 22. The primary ou...
Subjects
free text keywords: A300 Clinical Medicine, C841 Health Psychology, C860 Neuropsychology, /dk/atira/pure/researchoutput/pubmedpublicationtype/D016428, Journal Article, /dk/atira/pure/subjectarea/asjc/2700/2738, Psychiatry and Mental health, /dk/atira/pure/subjectarea/asjc/2800/2803, Biological Psychiatry, C800, RC0321, Articles, BF, Clinical psychology, Psychiatry, medicine.medical_specialty, medicine, Psychological intervention, Cognitive therapy, medicine.medical_treatment, Cognitive behavioral therapy, Mental health, Insomnia, medicine.symptom, business.industry, business, Randomized controlled trial, law.invention, law, Paranoia, Population, education.field_of_study, education
Related Organizations
Funded by
WT| Sleep and Circadian Neuroscience Institute (SCNi)
Project
  • Funder: Wellcome Trust (WT)
  • Project Code: 098461
  • Funding stream: Neuroscience and Mental Health
37 references, page 1 of 3

1 Harvey AG, Murray G, Chandler R, Soehner A. Sleep disturbance as transdiagnostic: consideration of neurobiological mechanisms. Clin Psychol Rev 2011; 31: 225-35.

2 Freeman D, Pugh K, Vorontsova N, Southgate L. Insomnia and paranoia. Schizophr Res 2009; 108: 280-84.

3 Reeve S, Sheaves B, Freeman D. The role of sleep dysfunction in the occurrence of delusions and hallucinations. Clin Psychol Rev 2015; 42: 96-115. [OpenAIRE]

4 Kendler KS, Campbell J. Interventionist causal models in psychiatry: repositioning the mind-body problem. Psychol Med 2009; 39: 881-87.

5 Dunn G, Emsley R, Liu H, et al. Evaluation and validation of social and psychological markers in randomised trials of complex interventions in mental health: a methodological research programme. Health Technol Assess 2015; 19: 1-115.

6 Emsley R, Dunn G, White IR. Mediation and moderation of treatment efects in randomised controlled trials of complex interventions. Stat Methods Med Res 2010; 19: 237-70.

7 Taylor M, Gregory A, Freeman D, Ronald A. Do sleep disturbances and psychotic experiences in adolescence share genetic and environmental influences? J Abnorm Psychol 2015; 124: 674-84.

8 Sheaves B, Porcheret K, Tsanas A, et al. Insomnia, nightmares and chronotype as markers of risk for severe mental illness. Sleep 2016; 39: 173-81.

9 Qaseem A, Kansagara D, Forciea M, Cooke M, Denberg T. Management of chronic insomnia disorder in adults: a clinical practice guideline from the American College of Physicians. Ann Intern Med 2016; 165: 125-33. [OpenAIRE]

10 Ritterband L, Thorndike F, Ingersoll K, et al. Efect of a web-based cognitive behaviour therapy for insomnia intervention with a 1-year follow-up: a randomized clinical trial. JAMA Psychiatry 2017; 74: 68-75. [OpenAIRE]

11 Espie C, Kyle S, Williams C, et al. A randomized, placebo-controlled trial of online cognitive behavioral therapy for chronic insomnia disorder delivered via an automated media-rich web application. Sleep 2012; 35: 769-81. [OpenAIRE]

12 Christensen H, Batterham P, Gosling J, et al. Efectiveness of an online insomnia program (SHUTi) for prevention of depressive episodes (the GoodNight Study): a randomised controlled trial. Lancet Psychiatry 2016; 3: 333-41.

13 Freeman D, Waite F, Startup H, et al. Eficacy of cognitive behavioural therapy for sleep improvement in patients with persistent delusions and hallucinations (BEST): a prospective, assessor-blind, randomised controlled pilot study. Lancet Psychiatry 2015; 2: 975-83.

14 Bilderbeck A, Atkinson L, McMahon H, et al. Psychoeducation and online mood tracking for patients with bipolar disorder. J Afect Disord 2016; 205: 245-51. [OpenAIRE]

15 Freeman D, Sheaves B, Goodwin G, et al. Efects of cognitive behavioural therapy for insomnia on the mental health of university students. Trials 2015; 16: 236.

37 references, page 1 of 3
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