International Criteria for Acute Kidney Injury: Advantages and Remaining Challenges

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Selby, Nicholas M. ; Fluck, Richard J. ; Kolhe, Nitin V. ; Taal, Maarten W. (2016)
  • Publisher: Public Library of Science
  • Journal: PLoS Medicine, volume 13, issue 9 (issn: 1549-1277, eissn: 1549-1676)
  • Related identifiers: pmc: PMC5021257, doi: 10.1371/journal.pmed.1002122
  • Subject: Hospitals | Chronic Kidney Disease | Biology and Life Sciences | Anatomy | Urine | Biomarkers | Physiology | Pathology and Laboratory Medicine | Kidneys | Body Fluids | Etiology | Nephrology | Creatinine | Health Care Facilities | Biochemistry | Essay | Medicine and Health Sciences | Renal System | Health Care
    mesheuropmc: urologic and male genital diseases | urogenital system | female genital diseases and pregnancy complications

• Acute Kidney Injury (AKI) is defined using widely accepted international criteria that are based on changes in serum creatinine concentration and degree of oliguria.\ud • AKI, when defined in this way, has a strong association with poor patient outcomes, including high mortality rates and longer hospital admissions with increased resource utilisation and subsequent chronic kidney disease.\ud • The detection of AKI using current criteria can assist with AKI diagnosis and stratification of individual patient risk.\ud • The diagnosis of AKI requires clinical judgement to integrate the definition of AKI with the clinical situation, to determine underlying cause of AKI, and to take account of factors that may affect performance of current definitions.
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