Dissection of the genetics of Parkinson's disease identifies an additional association 5 ' of SNCA and multiple associated haplotypes at 17q21

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Spencer, CCA; Plagnol, V; Strange, A; Gardner, M; Paisan-Ruiz, C; Band, G; Barker, RA; Bellenguez, C; Bhatia, K; Blackburn, H; Blackwell, JM; Bramon, E; Brown, MA; Burn, D; Casas, JP; Chinnery, PF; Clarke, CE; Corvin, A; Craddock, N; Deloukas, P; Edkins, S; Evans, J; Freeman, C; Gray, E; Hardy, J; Hudson, G; Hunt, S; Jankowski, J; Langford, C; Lees, AJ; ... view all 49 authors
(2011)
  • Publisher: Oxford University Press (OUP)

We performed a genome-wide association study (GWAS) in 1705 Parkinson's disease (PD) UK patients and 5175 UK controls, the largest sample size so far for a PD GWAS. Replication was attempted in an additional cohort of 1039 French PD cases and 1984 controls for the 27 re... View more
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