A C-terminal amphipathic helix is necessary for the in-vivo tubule-shaping function of plant reticulon

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Breeze, Emily; Dzimitrowicz, Natasha; Kriechbaumer, Verena; Brooks, Rhiannon; Botchway, Stanley W.; Brady, Jacob P.; Hawes, Chris; Dixon, Ann M.; Schnell, Jason R.; Fricker, Mark D.; Frigerio, Lorenzo;

Reticulons (RTNs) are a class of endoplasmic reticulum (ER) membrane proteins that are capable of maintaining high membrane curvature, thus helping shape the ER membrane into tubules. The mechanism of action of RTNs is hypothesized to be a combination of wedging, result... View more
  • References (1)

    Hawes C, Kiviniemi P, Kriechbaumer V (2015) The endoplasmic reticulum: A dynamic and well-connected organelle. J Integr Plant Biol 57(1):50-62.

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