Par3 integrates Tiam1 and phosphatidylinositol 3-kinase signaling to change apical membrane identity

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Ruch, Travis R.; Bryant, David M.; Mostov, Keith E.; Engel, Joanne N.; Yap, Alpha;
  • Publisher: American Society for Cell Biology

Pathogens can alter epithelial polarity by recruiting polarity proteins to the apical\ud membrane, but how a change in protein localization is linked to polarity disruption is not\ud clear. In this study, we used chemically induced dimerization to rapidly relocalize pro... View more
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