Efficacy evaluation of iclaprim in a neutropenic rat lung infection model with methicillin-resistant Staphylococcus aureus entrapped in alginate microspheres

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Huang, DB; Morrissey, I; Murphy, T; Hawser, S; Wilcox, MH;
(2018)
  • Publisher: Springer Verlag

The objective of this study was to demonstrate the efficacy of iclaprim in a neutropenic rat lung infection model with methicillin-resistant Staphylococcus aureus (MRSA) entrapped in alginate beads. An inoculum of 5.25 × 10⁵ colony-forming units (CFU)/mL of S. aureus st... View more
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