Informing efficient randomised controlled trials: Exploration of challenges in developing progression criteria for internal pilot studies

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Avery, KNL; Williamson, PR; Gamble, C; Francischetto, EOC; Metcalfe, C; Davidson, P; Williams, H; Blazeby, JM; Internal Pilot Trials Workshop,; Hubs for Trials Methodology Research,;
  • Publisher: BMJ Publishing Group
  • Subject:
    mesheuropmc: education

Objectives: Designing studies with an internal pilot phase may optimise the use of pilot work to inform more efficient randomised controlled trials (RCTs). Careful selection of preagreed decision or 'progression' criteria at the juncture between the internal pilot and m... View more
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