Phytochemicals in regulating fatty acid β-oxidation: Potential underlying mechanisms and their involvement in obesity and weight loss

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Rupasinghe, Vasantha; Sekhhon-Loodu, Satvir; Mantso, Theodora; Panagiotidis, Mihalis;
(2016)

Excessive accumulation of fat as the result of more energy intake and less energy expenditure is known as obesity. Lipids are essential components in the human body and are vital for maintaining homeostasis and physiological as well as cellular metabolism. Fatty acid sy... View more
  • References (17)
    17 references, page 1 of 2

    36) Farhat, G., Drummond, S., Fyfe, L,. Al-Dujaili. E.A.S. (2014). Dark Chocolate: An Obesity Paradox or a Culprit for Weight Gain? Phytother Res, 28, 791-797.

    37) Faulds, M.H., Dahlman, W.K. (2012). Metabolic diseases and cancer risk. Curr Opin Oncol, 24, 58-61.

    38) Field, D.T., Williams, C.M., Butler, L.T. (2011). Consumption of cocoa flavanols results in an acute improvement in visual and cognitive functions. Physiol Behav, 103, 255-260.

    39) Filozof, C.M., Murua, C., Sanchez, M.P., Brailovsky, C., Perman, M., Gonzalez, C.D., et al. (2000). Low plasma leptin concentration and low rates of fat oxidation in weight-stable post-obese subjects. Obesity Research, 8, 205-210.

    40) Friedman, MI. (2007). Obesity and the hepatic control of feeding behavior. Drug News Perspect 20, 573-578.

    41) Galleano, M., Oteiza, P., Fraga, C. (2009). Cocoa, chocolate and cardiovascular disease. J Cardiovasc Pharmacol, 54, 483-490.

    42) Goldwasser, J., Cohen, P.Y., Yang, E., Balaguer, P., Yarmush, M.L., Nahmias, Y. (2010). Transcriptional regulation of human and rat hepatic lipid metabolism by the grapefruit flavonoid naringenin: role of PPARalpha, PPARgamma and LXRalpha. PLoS One, 5, e12399.

    43) Gong, D.W., Monemdjou, S., Gavrilova, O., Leon, L.R., Marcus-Samuels, B., et al. (2000). Lack of obesity and normal response to fasting and thyroid hormone in mice lacking uncoupling protein-3. J Biol Chem, 275, 16251-16257.

    44) González-Castejón, M., & Rodriguez-Casado, A. (2011). Dietary phytochemicals and their potential effects on obesity: a review. Pharmacol Research, 64, 438-455.

    61) Hurley, R.L., Anderson, K.A., Franzone, J.M., Kemp, B.E., Means, A.R., Witters, L.A. (2005). The Ca2+/calmodulin-dependent protein kinase kinases are AMP-activated protein kinase kinases. J Biol Chem, 280, 29060-29066.

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