The malaria parasite egress protease SUB1 is a calcium-dependent redox switch subtilisin.

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Withers-Martinez, C; Strath, M; Hackett, F; Haire, LF; Howell, SA; Walker, PA; Christodoulou, E; Evangelos, C; Dodson, GG; Blackman, MJ;
  • Publisher: Nature Research (part of Springer Nature)
  • Subject:
    mesheuropmc: parasitic diseases

Malaria is caused by a protozoan parasite that replicates within an intraerythrocytic parasitophorous vacuole. Release (egress) of malaria merozoites from the host erythrocyte is a highly regulated and calcium-dependent event that is critical for disease progression. Mi... View more
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