Theory and practice of optimal mutation rate control in Hamming spaces of DNA sequences

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Belavkin, Roman V.; Channon, Alastair; Aston, Elizabeth; Aston, John; Knight, Christopher;
  • Publisher: MIT Press

We investigate the problem of optimal control of mutation by asexual self-replicating organisms represented by points in a metric space. We introduce the notion of a relatively monotonic fitness landscape and consider a generalisation of Fisher's geometric model of adap... View more
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