Long-Term Effects of the Periconception Period on Embryo Epigenetic Profile and Phenotype: The Role of Stress and How This Effect Is Mediated

Article English OPEN
Ord, J.; Fazeli, A.; Watt, P.J.;
  • Publisher: Springer

Stress represents an unavoidable aspect of human life, and pathologies associated with dysregulation of stress mechanisms - particularly psychiatric disorders - represent a significant global health problem. While it has long been observed that levels of stress experien... View more
  • References (59)
    59 references, page 1 of 6

    Aberg KM, Radek KA, Choi E-H, et al (2007) Psychological stress downregulates epidermal antimicrobial peptide expression and increases severity of cutaneous infections in mice. J Clin Invest 117:3339 3349. doi: 10.1172/JCI31726

    Alt SR, Turner JD, Klok MD, et al (2010) Differential expression of glucocorticoid receptor transcripts in major depressive disorder is not epigenetically programmed. Psychoneuroendocrinology 35:544 556. doi: 10.1016/j.psyneuen.2009.09.001

    Ariyomo TO, Carter M, Watt PJ (2013) Heritability of boldness and aggressiveness in the zebrafish. Behav Genet 43:161 167. doi: 10.1007/s10519-013-9585-y

    Arrant AE, Schramm-Sapyta NL, Kuhn CM (2013) Use of the light/dark test for anxiety in adult and adolescent male rats. Behav Brain Res 256:119 127. doi: 10.1016/j.bbr.2013.05.035

    Babiak I (2014) MicroRNA in teleost fish. Genome Biol Evol 6:1911 1937. doi: 10.1093/gbe/evu151

    Barbazanges A, Piazza P V, Le Moal M, Maccari S (1996) Maternal glucocorticoid secretion mediates long-term effects of prenatal stress. J Neurosci 16:3943 9.

    Barton B a (2002) Stress in fishes: a diversity of responses with particular reference to changes in circulating corticosteroids. Integr Comp Biol 42:517 525. doi: 10.1093/icb/42.3.517

    Blondeau B, Lesage J, Czernichow P, et al (2001) Glucocorticoids impair fetal beta-cell development in rats. Am J Physiol Endocrinol Metab 281:E592-9. doi: 10.1016/0024-3205(90)90607-s

    Bourin M, Hascoët M (2003) The mouse light/dark box test. Eur J Pharmacol 463:55 65. doi:

    Brown AS, Van Os J, Driessens C, et al (2000) Further evidence of relation between prenatal famine and major affective disorder. Am J Psychiatry 157:190 195. doi: 10.1176/appi.ajp.157.2.190

  • Related Research Results (1)
    Inferred by OpenAIRE
    Androgen-Responsive MicroRNAs in Mouse Sertoli Cells (2016)
  • Metrics
Share - Bookmark