High Throughput siRNA Screening Identifies Phosphatidylinositol 3-kinase Class II Alpha as Important for Production of Human Cytomegalovirus Virions.

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Polachek, WS; Moshrif, HF; Franti, M; Coen, DM; Sreenu, VB; Strang, BL;
  • Publisher: American Society for Microbiology
  • Subject:
    mesheuropmc: biochemical phenomena, metabolism, and nutrition | viruses

High throughput siRNA screening is a useful methodology to identify cellular factors required for virus replication. Here we utilized a high throughput siRNA screen based on detection of a viral antigen by microscopy to interrogate cellular protein kinases and phosphata... View more
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