The functions of the retrosplenial cortex
Hindley, Emma Logan
The functions of the retrosplenial cortex are not clearly understood, and the two current theories of retrosplenial cortex function, the translation and integration theories, are frequently very difficult to distinguish from each other, particularly in the spatial domain. The principal goal of this thesis was to differentiate between the integration and translation theories, and to explore the functions of the retrosplenial cortex in tasks that minimise or remove spatial demands, particularly navigation. \ud \ud The work presented in this thesis demonstrates that the retrosplenial cortex is involved in tasks extending beyond the spatial domain into executive functions and cross--‐modal processing. The retrosplenial cortex has been shown to be required for visually determining location in an environment, in the absence of self--‐generated navigational cues. Further evidence has been presented for the differing roles of the retrosplenial sub--‐regions, which appear to work in conjunction with each other to combine information received from different sensory modalities. However, further work is required to fully understand the ways in which these areas work together and with other areas of the brain, and the implications that dysfunction in this area has for human cognition.