Connective tissue structure of the tree shrew optic nerve and associated ageing changes

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Albon, Julie; Farrant, Sarah; Akhtar, Saeed; Young, Robert David; Boulton, Michael Edwin; Smith, Gillian Michelle; Taylor, Martin; Guggenheim, Jeremy Andrew; Morgan, James Edwards;
(2007)
  • Publisher: Association for Research in Vision and Ophthalmology
  • Identifiers: doi: 10.1167/iovs.06-0084
  • Subject:
    mesheuropmc: eye diseases | genetic structures | sense organs

purpose. To identify the structure and composition of the tree shrew optic nerve to determine its potential as a model for glaucoma.\ud \ud methods. Tree shrew optic nerves, aged 4 weeks to 5 years, were wax or cryoembedded for analysis of overall morphology and cellula... View more
  • References (39)
    39 references, page 1 of 4

    1. Minckler DS, Bunt AH, Johanson GW. Orthograde and retrograde axoplasmic transport during acute ocular hypertension in the monkey. Invest Ophthalmol Vis Sci. 1977;16:426 - 441.

    2. Quigley HA, Anderson DR. Distribution of axonal transport blockade by acute intraocular pressure elevation in the primate optic nerve head. Invest Ophthalmol Vis Sci. 1977;16:640 - 644.

    3. Quigley HA, Addicks EM. Chronic experimental glaucoma in primates. II. Effect of extended intraocular pressure elevation on optic nerve head and axonal transport. Invest Ophthalmol Vis Sci. 1980;19:137-152.

    4. Quigley HA, Addicks EM, Green WR, Maumenee AE. Optic nerve damage in human glaucoma. II. The site of injury and susceptibility to damage. Arch Ophthalmol. 1981;99:635- 649.

    5. Bellezza AJ, Rintalan CJ, Thompson HW, Downs JC, Hart RT, Burgoyne CF. Deformation of the lamina cribrosa and anterior scleral canal wall in early experimental glaucoma. Invest Ophthalmol Vis Sci. 2003;44:623- 637.

    6. Quigley HA, Hohman RM, Addicks EM, Massof RW, Green WR. Morphologic changes in the lamina cribrosa correlated with neural loss in open-angle glaucoma. Am J Ophthalmol. 1983;95:673- 691.

    7. Quigley HA, Dorman-Pease ME, Brown AE. Quantitative study of collagen and elastin of the optic nerve head and sclera in human and experimental monkey glaucoma. Curr Eye Res. 1991;10:877- 888.

    8. Johnson EC, Morrison JC, Farrell S, Deppmeier L, Moore CG, McGinty MR. The effect of chronically elevated intraocular pressure on the rat optic nerve head extracellular matrix. Exp Eye Res. 1996;62:663- 674.

    9. Morrison JC, Johnson EC, Cepurna W, Jia L. Understanding mechanisms of pressure-induced optic nerve damage. Prog Retin Eye Res. 2005;24:217-240.

    10. Quigley HA. Number of people with glaucoma worldwide. Br J Ophthalmol. 1996;80:389 -393.

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