Different roles for aspartates and glutamates for cation permeation in bacterial sodium channels

Article English OPEN
Guardiani, Carlo; Fedorenko, Olena A.; Khovanov, Igor A.; Roberts, Stephen K.;

A key driving force for ion channel selectivity is represented by the negative charge of the Selectivity Filter carried by aspartate (D) and glutamate (E) residues. However, the structural effects and specific properties of D and E residues have not been extensively stu... View more
Share - Bookmark