Synthesis, biological evaluation and SAR study of novel pyrazole analogues as inhibitors of Mycobacterium tuberculosis

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Castagnolo, Daniele; de Logu, Alessandro; Radi, Marco; Bechi, Beatrice; Manetti, Fabrizio; Magnani, Matteo; Supino, Sibilla; Meleddu, Rita; Chisu, Lorenza; Botta, Maurizio;

As a continuation of our previous work that turned toward the identification of antimycobacterial compounds with innovative structures, two series of pyrazole derivatives were synthesized by parallel solution-phase synthesis and were assayed as inhibitors of Mycobacteri... View more
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