publication . Article . Other literature type . 2018

Rates of HIV-1 superinfection and primary HIV-1 infection are similar in female sex workers in Uganda

Deogratius Ssemwanga;
Open Access
  • Published: 13 Nov 2018 Journal: AIDS, volume 28, pages 2,147-2,152 (issn: 0269-9370, Copyright policy)
  • Publisher: Ovid Technologies (Wolters Kluwer Health)
  • Country: United Kingdom
Abstract
OBJECTIVE To determine and compare the rates of HIV superinfection and primary HIV infection in high-risk female sex workers (FSWs) in Kampala, Uganda. DESIGN A retrospective analysis of individuals who participated in a clinical cohort study among high-risk FSWs in Kampala, Uganda. METHODS Plasma samples from HIV-infected FSWs in Kampala, Uganda were examined with next-generation sequencing of the p24 and gp41HIV genomic regions for the occurrence of superinfection. Primary HIV incidence was determined from initially HIV-uninfected FSWs from the same cohort, and incidence rate ratios were compared. RESULTS The rate of superinfection in these women (7/85; 3.4/10...
Subjects
Medical Subject Headings: virus diseasesparasitic diseases
free text keywords: Immunology, Immunology and Allergy, Infectious Diseases, Incidence (epidemiology), Rate ratio, Superinfection, medicine.disease_cause, medicine, Virology, Retrospective cohort study, Population, education.field_of_study, education, Cohort, Cohort study, business.industry, business, HIV superinfection
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