publication . Other literature type . Article . 2004

ADHERENCE TO A SIX-DOSE REGIMEN OF ARTEMETHER-LUMEFANTRINE FOR TREATMENT OF UNCOMPLICATED PLASMODIUM FALCIPARUM MALARIA IN UGANDA

Fogg, Carole; Bajunirwe, Francis; Piola, Patrice; Biraro, Samuel; Checchi, Francesco; Kiguli, James; Namiiro, Proscovia; Musabe, Joy; Kyomugisha, Agnes; Guthmann, Jean-Paul;
  • Published: 01 Nov 2004
  • Publisher: American Society of Tropical Medicine and Hygiene
  • Country: United Kingdom
Abstract
Measuring baseline levels of adherence and identifying risk factors for non-adherence are important steps before the introduction of new antimalarials. In Mbarara in southwestern Uganda, we assessed adherence to artemether-lumefantrine (Coartem) in its latest World Health Organization blister formulation. Patients with uncomplicated Plasmodium falciparum malaria were prescribed artemether-lumefantrine and received an explanation of how to take the following five doses at home. A tablet count was made and a questionnaire was completed during a home visit. Among 210 analyzable patients, 21 (10.0%) were definitely or probably non-adherent, whereas 189 (90.0%) were ...
Subjects
Medical Subject Headings: parasitic diseases
free text keywords: Lumefantrine, chemistry.chemical_compound, chemistry, Regimen, Confidence interval, Surgery, medicine.medical_specialty, medicine, Immunology, Internal medicine, Artemether/lumefantrine, medicine.drug, Artemether, Odds ratio, business.industry, business, Malaria, medicine.disease, Population, education.field_of_study, education
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