Fine-mapping of the 1p11.2 breast cancer susceptibility locus

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Horne, H.N.; Chung, C.E.; Zhang, H.; Yu, K.; Prokunina-Olsson, L.; Michailidou, K.; Bolla, M.K.; Wang, Q.; Dennis, J.; Hopper, J.L.; Southey, M.C.; Schmidt, M.K.; Broeks, A.; Muir, K.; Lophatananon, A.; Fasching, P.A.; Beckmann, M.W.; Fletcher, O.; Johnson, N.; Sawyer, E.J.; Tomlinson, I.; Burwinkel, B.; Marme, F.; Guénel, P.; Truong, T.; Bojesen, S.E.; Flyger, H.; Benitez, J.; González-Neira, A.; Anton-Culver, H.; ... view all 115 authors
(2016)
  • Publisher: Public Library of Science

The Cancer Genetic Markers of Susceptibility genome-wide association study (GWAS) originally identified a single nucleotide polymorphism (SNP) rs11249433 at 1p11.2 associated with breast cancer risk. To fine-map this locus, we genotyped 92 SNPs in a 900kb region (120,50... View more
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