Narcolepsy is a relatively common neurological condition affecting the regulation of normal sleep/wake cycles leading to excessive daytime sleepiness (EDS). It is almost certainly under-recognised as it has a prevalence of 20–50 per 100,000 population and most cases hav... View more
1. Miller E, Andrews N, Stellitano L, Stowe J, Winstone AM, Shneerson J, Verity C. Risk of narcolepsy in children and young people receiving AS03 adjuvanted pandemic A/H1N1 2009 influenza vaccine: retrospective analysis. BMJ. 2013 Feb 26;346:f794.
2. American Academy of Sleep Medicine: International classification of sleep disorders Third edition (ICSD3). Darien IL. American Academy of Sleep Medicine; 2014.
3. Johns MW. A new method for measuring daytime sleepiness: the Epworth Sleepiness Scale. Sleep. 1991 Dec;14(6):540-5.
4. Prasad M, Setty G, Ponnusamy A, Hussain N, Desurkar A. Cataplectic facies: clinical marker in the diagnosis of childhood narcolepsy report of two cases. Pediatric neurology 2014;50:515-517.
5. Aurora RN, Lamm CI, Zak RS, Kristo DA, Bista SR, Rowley JA, Casey KR. Practice parameters for the non-respiratory indications for polysomnography and multiple sleep latency testing for children. Sleep 2012;35:1467-1473. -Focused Drug Development Initiative, Narcolepsy Report 2014. http://www.fda.gov/downloads/ForIndustry/UserFees/PrescriptionDrugUserFee/UCM40290 7.pdf
7. Blackwell JE, Alammar HA, Weighall AR, Kellar I, Nash HM. A systematic review of cognitive function and psychosocial well-being in school-age children with narcolepsy. Sleep Medicine Reviews. 2016 (in press)
8. Mignot EJM. A Practical guide to the Therapy of narcolepsy and hypersomnia syndromes Neurotherapeutics 2012; 9: 739-752
9. NHS England. Clinical commissioning policy: sodium oxybate for symptom control of narcolepsy with cataplexy (children). 2016. www.engage.england.nhs.uk/consultation/ clinical-commissioning-wave8/user_uploads/e09x03-policy-prop.pdf.
10. Narcolepsy UK (www.narcolepsy.org.uk) Heather Elphick, Teya Staniforth and Ruth Kingshott have no conflicts of interest. Jane Blackwell has received a 110 Anniversary Research Scholarship from The University of Leeds to fund her PhD in paediatric narcolepsy.