Lysophosphatidylcholine activates caspase-1 in microglia via a novel pathway involving two inflammasomes.

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Scholz, H; Eder, C;
  • Subject:
    mesheuropmc: lipids (amino acids, peptides, and proteins)

Inflammasomes regulate microglial caspase-1 activation and subsequent neuroinflammatory processes in brain pathology. In the present study, we have identified inflammasomes causing caspase-1 activation following stimulation of microglia with lysophosphatidylcholine (LPC... View more
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