Lysophosphatidylcholine activates caspase-1 in microglia via a novel pathway involving two inflammasomes.
Scholz, H; Eder, C;
mesheuropmc: lipids (amino acids, peptides, and proteins)
Inflammasomes regulate microglial caspase-1 activation and subsequent neuroinflammatory processes in brain pathology. In the present study, we have identified inflammasomes causing caspase-1 activation following stimulation of microglia with lysophosphatidylcholine (LPC... View more