publication . Thesis

Behavioural analysis of transgenic mice overexpressing gamma-synuclein

Salem, Hatem;
Open Access English
  • Country: United Kingdom
Abstract
The alpha-synucleinopathies is a diverse group of diseases characterised by\ud malfunctioning of alpha-synuclein protein. Parkinson’s disease is the most common\ud of all alpha-synucleinopathies.\ud Intracellular inclusions, like Lewy bodies and certain other abnormal structures are\ud the pathological hallmarks of this group of neurodegenerative diseases. The main\ud protein component of these structures is alpha-synuclien.\ud Alpha-synuclein is a member of the synuclein family, which consists of 3 closely\ud related proteins, alpha-, beta- and gamma-synucleins. Alpha-synuclein is more\ud extensively studied because of its direct involvement in human diseases, ...
Subjects
Medical Subject Headings: nervous system diseasesnervous systemanimal diseasesmental disorders
free text keywords: QH301
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