Detection of l-alanylaminopeptidase activity in microorganisms using fluorogenic self-immolative enzyme substrates

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Cellier, Marie; James, Arthur; Lowe, Jonathan; Orenga, Sylvain; Perry, John; Rasul, Ari; Stanforth, Stephen;
(2016)

A series of fluorogenic enzymatic substrates that incorporate a self-immolative spacer were synthesised for the purpose of identifying l-alanylaminopeptidase activity in microorganisms in agar media. These substrates resulted in the generation of fluorescent microorgani... View more
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