Filaggrin null mutations are associated with increased asthma exacerbations in children and young adults

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Basu, K; Palmer, C N A; Lipworth, B J; Irwin, W H; Terron-Kwiatkowski, A; Zhao, Y; Liao, H; Smith, F J D; Mitra, A; Mukhopadhyay, S;
(2008)

Background: Filaggrin (FLG) null mutations are important genetic predisposing factors for atopic asthma and have recently been shown to influence controller and reliever medication needs in asthmatic children. Our objective was to study the role of FLG null alleles in a... View more
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