Tonic modulation of spinal hyperexcitability by the\ud endocannabinoid receptor system in a rat model of\ud osteoarthritis pain

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Sagar, Devi Rani; Staniaszek, Lydia E.; Okine, Bright N.; Woodhams, Stephen; Norris, Leonie M.; Pearson, Richard G.; Garle, Michael J.; Alexander, Stephen P.H.; Bennett, Andrew J.; Barrett, David A.; Kendall, David A.; Scammell, Brigitte E.; Chapman, Victoria;
(2010)
  • Publisher: Wiley
  • Identifiers: doi: 10.1002/art.27698
  • Subject:
    mesheuropmc: lipids (amino acids, peptides, and proteins)

Objective. To investigate the impact of an experimental\ud model of osteoarthritis (OA) on spinal nociceptive\ud processing and the role of the inhibitory endocannabinoid\ud system in regulating sensory processing at the\ud spinal level.\ud Methods. Experimental OA was ... View more
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