Flavonoids as modulators of memory and learning: molecular\ud interactions resulting in behavioural effects

Article English OPEN
Rendeiro, Catarina; Guerreiro, Joao D.T.; Williams, Claire; Spencer, Jeremy;
(2012)

There is considerable interest in the potential of a group of dietary-derived phytochemicals known as flavonoids in modulating neuronal function and thereby influencing memory, learning and cognitive function. The present review begins by detailing the molecular events ... View more
  • References (235)
    235 references, page 1 of 24

    1. Parrott MD & Greenwood CE (2007) Dietary influences on cognitive function with aging: from high-fat diets to healthful eating. Ann N Y Acad Sci 1114, 389-397.

    2. Gomez-Pinilla F (2008) Brain foods: the effects of nutrients on brain function. Nat Rev Neurosci 9, 568-578.

    3. Greenwood CE & Winocur G (2005) High-fat diets, insulin resistance and declining cognitive function. Neurobiol Aging 26, Suppl. 1, 42-45.

    4. Molteni R, Barnard RJ, Ying Z et al. (2002) A high-fat, refined sugar diet reduces hippocampal brain-derived neurotrophic factor, neuronal plasticity, and learning. Neuroscience 112, 803-814.

    5. Ingram DK, Weindruch R, Spangler EL et al. (1987) Dietary restriction benefits learning and motor performance of aged mice. J Gerontol 42, 78-81.

    6. Johnson JB, Summer W, Cutler RG et al. (2007) Alternate day calorie restriction improves clinical findings and reduces markers of oxidative stress and inflammation in overweight adults with moderate asthma. Free Radic Biol Med 42, 665-674.

    7. Letenneur L, Proust-Lima C, Le Gouge A et al. (2007) Flavonoid intake and cognitive decline over a 10-year period. Am J Epidemiol 165, 1364-1371.

    8. Patel AK, Rogers JT & Huang X (2008) Flavanols, mild cognitive impairment, and Alzheimer's dementia. Int J Clin Exp Med 1, 181-191.

    9. Beking K & Vieira A (2011) Flavonoid intake and disability-adjusted life years due to Alzheimer's and related dementias: a population-based study involving twentythree developed countries. Public Health Nutr 13, 1403- 1409.

    10. Nurk E, Refsum H, Drevon CA et al. (2009) Intake of flavonoid-rich wine, tea, and chocolate by elderly men and women is associated with better cognitive test performance. J Nutr 139, 120-127.

  • Related Organizations (4)
  • Metrics
Share - Bookmark