Rates of microfilarial production by Onchocerca volvulus are not cumulatively reduced by multiple ivermectin treatments.

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Bottomley, C; Isham, V; Collins, RC; Bas??ez, MG;
  • Publisher: Cambridge University Press (CUP)
  • Subject:
    mesheuropmc: parasitic diseases

Regular distribution of ivermectin reduces onchocerciasis transmission and morbidity by killing, within humans, the microfilarial stage of the parasite (microfilaricidal effect). In addition, ivermectin exerts a so-called embryostatic effect by which microfilarial produ... View more
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