STAT1 signaling is not regulated by a phosphorylation-acetylation switch

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Antunes, Filipa.; Marg, Andreas.; Vinkemeier, Uwe.;
  • Publisher: American Society for Microbiology

The treatment of cells with histone deacetylase inhibitors (HDACi) was reported to reveal the acetylation ofSTAT1 at lysine 410 and lysine 413 (O. H. Kra¨mer et al., Genes Dev. 20:473–485, 2006). STAT1 acetylation wasproposed to regulate apoptosis by facilitating bindin... View more
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