Hepatitis C virus NS5A targets the nucleosome assembly protein NAP1L1 to control the innate cellular response

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Çevik, Recep Emrah; Cesarec, Mia; Da Silva Filipe, Ana; Licastro, Danilo; McLauchlan, John; Marcello, Alessandro;
(2017)
  • Publisher: American Society for Microbiology
  • Subject:
    mesheuropmc: biochemical phenomena, metabolism, and nutrition | viruses | virus diseases | digestive system diseases

Hepatitis C virus (HCV) is a single-stranded positive-sense RNA hepatotropic virus. Despite cellular defenses, HCV is able to replicate in hepatocytes and to establish a chronic infection that could lead to severe complications and hepatocellular carcinoma. An important... View more
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