An investigation of the impact of CD4+CD25+ regulatory T cells on immune responses induced in vivo

0044 English OPEN
Richards, Hannah Elizabeth;
  • Subject: R1
    mesheuropmc: chemical and pharmacologic phenomena | hemic and immune systems

CD4+CD25+ regulatory T cells (Treg) are known to inhibit T cell responses however their site of action and whether they suppress other immune responses has not been well characterised. Using a model of tumour rejection involving a melanoma cell line expressing Fas ligan... View more
  • References (206)
    206 references, page 1 of 21

    Asano, M., Toda, M., Sakaguchi, N. and Sakaguchi, S. (1996). Autoimmune disease as a consequence of developmental abnormality of a T cell subpopulation. JExp Med 184(2): 387-396.

    Asea, A., Rehli, M., Kabingu, E., Boch, J.A., Bare, O., Auron, P.E., Stevenson, M.A. and Calderwood, S.K. (2002). Novel signal transduction pathway utilized by extracellular HSP70: role of toll-like receptor (TLR) 2 and TLR4. J Biol Chem 277(17): 15028-15034.

    Baecher-Allan, C., Brown, J.A., Freeman, G.J. and Hafler, D.A. (2001). CD4+CD25high regulatory cells in human peripheral blood. J Immunol 167(3): 1245-1253.

    Banchereau, J. and Steinman, R.M. (1998). Dendritic cells and the control of immunity. Nature 392(6673): 245-252.

    Baroja, M.L., Luxenberg, D., Chau, T., Ling, V., Strathdee, C.A., Carreno, B.M. and Madrenas, J. (2000). The inhibitory function of CTLA-4 does not require its tyrosine phosphorylation. J Immunol 164(1): 49-55.

    Baumgarth, N. and Kelso, A. (1996a). Functionally distinct T cells in three compartments of the respiratory tract after influenza virus infection. Eur J Immunol 26(9): 2189- 2197.

    Baumgarth, N. and Kelso, A. (1996b). In vivo blockade of gamma interferon affects the influenza virus-induced humoral and the local cellular immune response in lung tissue. J Virol 70(7): 4411-4418.

    Beckstead, J.H. (1994). A simple technique for preservation of fixation-sensitive antigens in paraffin-embedded tissues. JHistochem Cytochem 42(8): 1127-1134.

    Behrens, C.K., Igney, F.H., Arnold, B., Moller, P. and Krammer, P.H. (2001). CD95 ligand-expressing tumors are rejected in anti-tumor TCR transgenic perforin knockout mice. J Immunol 166(5): 3240-3247.

    Belghith, M., Bluestone, J.A., Barriot, S., Megret, J., Bach, J.F. and Chatenoud, L. (2003). TGF-beta-dependent mechanisms mediate restoration of self-tolerance induced by antibodies to CD3 in overt autoimmune diabetes. Nat Med 9(9): 1202- 1208.

  • Similar Research Results (1)
  • Metrics
Share - Bookmark