Flexible nanoassembly for sequestering non-native proteins
Clark, Alice R.
- Publisher: Elsevier
(issn: 0969-2126, vol:
Molecular Biology | bcs | Structural Biology
A crystal structure of a yeast small heat shock protein reported by Hanazono and colleagues in this issue of Structure reveals the versatility of the α-crystallin domain dimer for building assemblies of different size and symmetry. The domains assemble into a vessel filled with hydrophobic sequence extensions enriched with phenylalanines.