publication . Article . Other literature type . 2017

Genetics and other factors in the aetiology of female pattern hair loss

Redler, Silke; Messenger, Andrew G.; Betz, Regina C.;
Open Access English
  • Published: 01 Jun 2017
  • Publisher: Wiley
  • Country: United Kingdom
Abstract
Pattern hair loss is the most common form of hair loss in both women and men. Male pattern hair loss, also termed male androgenetic alopecia (M-AGA), is an androgen-dependent trait that is predominantly genetically determined. Androgen-mediated mechanisms are probably involved in FPHL in some women but the evidence is less strong than in M-AGA; and other non-androgenic pathways, including environmental influences, may contribute to the aetiology. Genome-wide association studies (GWASs) have identified several genetic loci for M-AGA and have provided better insight into the underlying biology. However, the role of heritable factors in female pattern hair loss (FP...
Subjects
free text keywords: Trait, Etiology, Molecular genetics, medicine.medical_specialty, medicine, Biology, Genetic association, Gene, Candidate gene, Hair loss, medicine.disease, Genetics, Locus (genetics)
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