publication . Article . 2007

Association of telomere shortening with impaired glucose tolerance and diabetic macroangiopathy

Adaikalakoteswari, A; Balasubramanyam, M; Ravikumar, R; Deepa, R; Mohan, V;
Open Access
  • Published: 01 Nov 2007 Journal: Atherosclerosis, volume 195, pages 83-89 (issn: 0021-9150, Copyright policy)
  • Publisher: Elsevier BV
  • Country: Italy
Objective: Shortening of telomere length has been reported in several conditions including Type 2 diabetes and atherosclerosis. The aims of this study were (1) to assess whether telomere shortening occurs at the stage of pre-diabetes, i.e., impaired glucose tolerance (IGT) and (2) whether telomere shortening was greater in Type 2 diabetic subjects with atherosclerotic plaques.\ud \ud Methods: Subjects with impaired glucose tolerance (IGT) (n = 30), non-diabetic control subjects (n = 30), Type 2 diabetic patients without (n = 30) and with atherosclerotic plaques (n = 30) were selected from the Chennai Urban Rural Epidemiology Study (CURES), an ongoing epidemiolog...
free text keywords: Diabetes mellitus, medicine.disease, medicine, C-reactive protein, biology.protein, biology, Population, education.field_of_study, education, Glycated hemoglobin, chemistry.chemical_compound, chemistry, TBARS, business.industry, business, Impaired glucose tolerance, Internal medicine, medicine.medical_specialty, Type 2 diabetes, Endocrinology, Cholesterol
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