Emerging role of the calcium-activated, small conductance, SK3 K + channel in distal tubule function: Regulation by TRPV4

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Berrout, J; Mamenko, M; Zaika, OL; Chen, L; Zang, W; Pochynyuk, O; O'Neil, RG;
  • Publisher: Public Library of Science

The Ca2+-activated, maxi-K (BK) K+ channel, with low Ca2+-binding affinity, is expressed in the distal tubule of the nephron and contributes to flow-dependent K+ secretion. In the present study we demonstrate that the Ca2+-activated, SK3 (KCa2.3) K + channel, with high ... View more
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