Investigation of platinum drug mode of action and resistance using yeast and human neuroblastoma cells as model systems

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Sanders, Lara Clare;
  • Subject: Q

The platinum-based cytotoxic chemotherapeutics cisplatin, carboplatin, and oxaliplatin are widely used as anti-cancer drugs, but their efficacy is limited by the occurrence of resistance. The mechanisms of actions of these drugs as well as the mechanisms underlying resi... View more
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