Long-term fluctuation in short-wavelength automated perimetry in glaucoma suspects and glaucoma patients

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Hutchings, Natalie ; Hosking, Sarah L. ; Wild, John Millington ; Flanagan, John (2001)
  • Publisher: Association for Research in Vision and Ophthalmology
  • Subject: RE
    mesheuropmc: eye diseases | genetic structures | sense organs

PURPOSE. To determine the magnitude of the homogenous, LF(Ho), and the heterogeneous, LF(He), components of the long-term fluctuation (LF) in glaucoma suspects and in stable primary open angle glaucoma (POAG) patients undergoing short-wavelength automated perimetry (SWAP) and to compare the magnitude of the SWAP LF components with those elicited by standard white-on-white (W-W) perimetry. \ud \ud METHODS. The sample comprised 33 glaucoma suspects and 17 patients with early-to-moderate stable POAG who underwent W-W perimetry and SWAP at each of six visits over a mean period of 12.75 months (SD, 2.29). The LF(Ho), LF(He), and error components of the long-term fluctuation were determined between the third and seventh visual field examinations. The intervening visual field examinations and the optic nerve head parameters, derived both by stereo observation and by the Heidelberg Retinal Tomograph, were used to confirm stability over the follow-up period. \ud \ud RESULTS. The LF(Ho) and LF(He) components were larger in the POAG patients than in the glaucoma suspects for both W-W perimetry and SWAP; the magnitude was independent of the depth of defect and of the short-term fluctuation. All three components of long-term fluctuation were greater for SWAP than for W-W perimetry, both in the glaucoma suspects and in the POAG patients. \ud \ud CONCLUSIONS. SWAP exhibits greater long-term fluctuation than white-on-white perimetry. The usefulness of SWAP will be limited if the extent of this variability is not overcome in future statistical procedures developed to detect progressive visual field loss.
  • References (33)
    33 references, page 1 of 4

    1. Sample PA, Haegerstrom-Portnoy G, Adams AJ. Optimum parameters for short-wavelength automated perimetry. J Glaucoma. 1996; 5:375-383.

    2. Heron G, Adams AJ, Husted R. Central visual-fields for short wavelength sensitive pathways in glaucoma and ocular hypertension. Invest Ophthalmol Vis Sci. 1988;29:64 -72.

    3. de Jong LAMS, Snepvangers CEJ, van den Berg TJ, Langerhorst CT. Blue-yellow perimetry in the detection of early glaucomatous damage. Doc Ophthalmol. 1990;75:303-314.

    4. Sample PA, Taylor JDN, Martinez GA, Lusky M, Weinreb RN. Short-wavelength color visual-fields in glaucoma suspects at risk. Am J Ophthalmol. 1993;115:225-233.

    5. Sample PA, Weinreb RN. Color perimetry for assessment of primary open-angle glaucoma. Invest Ophthalmol Vis Sci. 1990;31: 1869 -1875.

    6. Johnson CA, Adams AJ, Casson EJ, Brandt JD. Blue-on-yellow perimetry can predict the development of glaucomatous visual field loss. Arch Ophthalmol. 1993;111:645- 650.

    7. Johnson CA, Brandt JD, Khong AM, Adams AJ. Short-wavelength automated perimetry in low-, medium-, and high-risk ocular hypertensive eyes. Initial baseline results. Arch Ophthalmol. 1995;113: 70 -76.

    8. Kwon YH, Park HJ, Jap A, Ugurlu S, Caprioli J. Test-retest variability of blue-on-yellow perimetry is greater than white-on-white perimetry in normal subjects. Am J Ophthalmol. 1998;126:29 -36.

    9. Wild JM, Moss ID, Whitaker D, O'Neill EC. The statistical interpretation of blue-on-yellow visual field loss. Invest Ophthalmol Vis Sci. 1995;36:1398 -1410.

    10. Sample PA, Cook JN, Weinreb RN. Variability and sensitivity of short-wavelength color visual fields in normal and glaucoma eyes. In: Ophthalmic & Visual Optics/Noninvasive Assessment of the Visual System Technical Digest, 1993. Washington, DC: Optical Society of America; 1993:292-295.

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