Tc-99m-NTP 15-5 assessment of the early therapeutic response of chondrosarcoma to zoledronic acid in the Swarm rat orthotopic model

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Miot-Noirault, E.; David, E.; Vidal, A.; Peyrode, C.; Besse, S.; Dauplat, M-M.; Heymann, M-F.; Gouin, F.; Chezal, J-M.; Heymann, D.; Redini, F.;
  • Publisher: BioMed Central

Background: Since proteoglycans (PGs) appear as key partners in chondrosarcoma biology, PG-targeted imaging using the radiotracer 99mTc-N-(triethylammonium)-3-propyl-[15]ane-N5 (99mTc-NTP 15-5) developed by our group was previously demonstrated to be a good single-photo... View more
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