Background: Rapid tranquillisation is used when control of agitation, aggression or excitement is required. Throughout the UK there is no consensus over the choice of drugs to be used as first line treatment. The NICE guideline on the management of violent behaviour inv... View more
Aleman, A. and Kahn, R.S. (2001) Effects of the atypical antipsychotic risperidone on hostility and aggression in schizophrenia: A meta-analysis of controlled trials. European Neuropsychopharmacology. 11: 289 293.
Alexander, J., Tharyan, P., Adams, C., John, T., Mol, C. and Philip, J. (2004) Rapid tranquillisation of violent or agitated patients in a psychiatric emergency setting. Pragmatic randomised trial of intramuscular lorazepam versus haloperidol plus promethazine. British Journal of Psychiatry. 185: 63 69.
Battaglia, J., Moss, S., Rush, J., Kang, J., Mendoza, R., Leedom, L., Dubin, W., McGlynn, C. and Goodman, L. (1997) Haloperidol, lorazepam, or both for psychotic agitation? A multicenter, prospective double-blind, emergency department study. American Journal of Emergency Medicine. 15(4): 335 340.
Beer, M.D., Paton, C. and Pereira, S.M. (2001) Management of acutely disturbed behaviour. In: Beer, M.D, Pereira, S.M., Paton, C. (eds). Psychiatric Intensive Care. London: Greenwich Medical Media. p25.
Brier, A., Meehan, K., Birkett, M., David, S., Ferchland, I., Sutton, V., Taylor, C.C., Palmer, R., Dossenbach, M., Kiesler, G., Brook, S. and Wright, P. (2002) A doubleblind, placebo-controlled dose-response comparison of intramuscular olanzapine and haloperidol in the treatment of acute agitation in schizophrenia. Archive of General Psychiatry. 59: 441 448.
Broadstock, M. (2001) The Effectiveness and Safety of Drug Treatment for Urgent Sedation in Psychiatric Emergencies: A Critical Appraisal of the Literature. New Zealand Health Technology Assessment Report 2001; 4(1).
Brook, S., Lucey, J.V. and Gunn, K.P. (2000) Intramuscular ziprasidone compared with intramuscular haloperidol in the treatment of acute psychosis. Journal of Clinical Psychiatry. 61(12): 933 941.
Burgess, S. (1997) Emergency drug treatment of disturbed psychotic patients. Auditorium. 6(1): 28 30.
Corrigan, J.D. (1989) Development of a scale of assessment of agitation following traumatic brain injury. Journal of Clinical and Experimental Neuropsychology. 11(2): 261 277.
Cunnane, J.G. (1994) Drug management of disturbed behaviour by psychiatrists. Psychiatric Bulletin. 18: 138 139.