A novel bioactive derivative of eicosapentaenoic acid (EPA) suppresses intestinal tumor development in ApcΔ14/+ mice

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Nakanishi, M; Hanley, MP; Zha, R; Igarashi, Y; Hull, MA; Mathias, G; Sciavolino, F; Grady, JJ; Rosenberg, DW;
  • Publisher: Oxford University Press
  • Subject:
    mesheuropmc: lipids (amino acids, peptides, and proteins)

Familial adenomatous polyposis (FAP) is a genetic disorder characterized by the development of hundreds of polyps throughout the colon. Without prophylactic colectomy, most individuals with FAP develop colorectal cancer at an early age. Treatment with EPA in the free fa... View more
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