Identification of novel 2-(1H-Indol-1-yl)benzohydrazides CXCR4 ligands impairing breast cancer growth and motility

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Fedora, Grande; Ines, Barone; Francesca, Aiello; Brancale, Andrea; Cancellieri, Michela; Mariateresa, Badolato; Francesca, Chemi; Cinzia, Giordano; Valentina, Vircillo; Daniela, Bonofiglio; Antonio, Garofalo; Sebastiano, Ando; Stefania, Catalano;

Stromal-derived-factor-1 (SDF-1) and the G-protein-coupled receptor CXCR4 are involved in several physiological and pathological processes including breast cancer spread and progression. Several CXCR4 antagonists have currently reached advanced development stages as pot... View more
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