Genome-wide association studies of autoimmune vitiligo identify 23 new risk loci and highlight key pathways and regulatory variants

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Jin, Y.; Andersen, G.; Yorgov, D.; Ferrara, T.M.; Ben, S.; Brownson, K.M.; Holland, P.J.; Birlea, S.A.; Siebert, J.; Hartmann, A.; Lienert, A.; Luiten, R.M.; Wolkerstorfer, A.; Wietze van der Veen, J.P.; van Geel, N.; Lambert, J.; Bennett, D.C.; Taïeb, A.; Ezzedine, K.; Kemp, E.H.; Gawkrodger, D.J.; Weetman, A.P.; Koks, S.; Prans, E.; Kingo, K.; Karelson, M.; Wallace, M.R.; McCormack, W.T.; Overbeck, A.; Moretti, S.; ... view all 44 authors
(2016)
  • Publisher: Nature Publishing Group
  • Subject:
    mesheuropmc: skin and connective tissue diseases | integumentary system

Vitiligo is an autoimmune disease in which depigmented skin results from destruction of\ud skin melanocytes, with strong epidemiologic association with several other autoimmune\ud diseases. In previous linkage and genome-wide association studies (GWAS1, GWAS2),\ud we id... View more