Two dimensional population balance modelling of crystal growth behaviour under the influence of impurities

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Zhang, Y ; Liu, JJ ; Wan, J ; Wang, XZ (2015)
  • Publisher: Elsevier

This short communication investigates the impact of impurity on crystal growth behaviour in terms of crystal shape distribution. A two dimensional population balance model is applied to study the crystal shape changing behaviour in cooling crystallisation producing β-form L-glutamic acid crystals, in the presence and without the presence of an additive, L-phenylalanine. The simulation results were verified in experiments using a 1-litre crystalliser for crystallisation of L-glutamic acid.
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