Stress-triggered redox signalling: What’s in pROSpect?

Article English OPEN
Foyer, CH ; Noctor, G (2016)
  • Publisher: Wiley

Reactive oxygen species (ROS) have a profound influence on almost every aspect of plant biology. Here, we emphasize the fundamental, intimate relationships between light-driven reductant formation, ROS, and oxidative stress, together with compartment-specific differences in redox buffering and the perspectives for their analysis. Calculations of approximate H₂O₂ concentrations in the peroxisomes are provided, and based on the likely values in other locations such as chloroplasts, we conclude that much of the H₂O₂ detected in conventional in vitro assays is likely to be extracellular. Within the context of scant information on ROS perception mechanisms, we consider current knowledge, including possible parallels with emerging information on oxygen sensing. Although ROS can sometimes be signals for cell death, we consider that an equally important role is to transmit information from metabolism to allow appropriate cellular responses to developmental and environmental changes. Our discussion speculates on novel sensing mechanisms by which this could happen and how ROS could be counted by the cell, possibly as a means of monitoring metabolic flux. Throughout, we place emphasis on the positive effects of ROS, predicting that in the coming decades they will increasingly be defined as hallmarks of viability within a changing and challenging environment.
  • References (9)

    Foyer, C.H. (2015) Redox homeostasis: Opening up ascorbate transport. Nature Plants1, 14012.

    Foyer, C.H. & Noctor, G. (2009) Redox regulation in photosynthetic organisms: signaling, acclimation, and practical implications. Antioxidants & Redox Signaling11, 861-905.

    Foyer, C.H., Neukermans, J., Queval, G., Noctor, G. &Harbinson, J. (2012) Photosynthetic control of electron transport and the regulation of gene expression. Journal of Experimental Botany63,1637- 1661.

    Frottin, F., Espagne, C., Traverso, J.A., Mauve, C., Valot, B., Lelarge-Trouverie, C., Zivy, M., Noctor, G.,Meinnel, T. &Giglione, C. (2009) Cotranslational proteolysis dominates glutathione homeostasis for proper growth and development. The Plant Cell21, 3296-3314.

    Gibbs, D.J., Bacardit, J., Bachmair, A. &Holdsworth, M.J. (2014)The eukaryotic N-end rule pathway: conserved mechanisms and diverse functions. Trends in Cell Biology24, 603-611.

    Gomez L.D., NoctorG., Knight M. & FoyerC.H. (2004) Regulation of calcium signaling and gene expression by glutathione.Journal of Experimental Botany55, 1851-1859.

    Gomez-Cabrera, M.C., Domenech, E., Romagnoli, M., Arduini, A., Borras, C.,Pallardo, F.V., Sastre, J. & Vina, J. (2008)Oral administration of vitamin C decreases muscle mitochondrialbiogenesis and hampers training-induced adaptations in enduranceperformance. American Journal of Clinical Nutrition 87, 142-149.

    Grzam A., Martin M.N., Hell R. &Meyer A.J. (2007) -Glutamyl transpeptidase GGT4 initiates vacuolar degradation of glutathione S-conjugates in Arabidopsis. FEBS Letters581, 3131-3138.

    Gutscher, M., Sobotta, M.C., Wabnitz, G.H., Ballikaya, S., Meyer, A.J., Samstag, Y. & Dick, T.P. (2009) Proximity-based protein thiol oxidation by H2O2-scavenging peroxidases.Journal of Biological Chemistry284, 31532-31540.

  • Metrics
    0
    views in OpenAIRE
    0
    views in local repository
    85
    downloads in local repository

    The information is available from the following content providers:

    From Number Of Views Number Of Downloads
    White Rose Research Online - IRUS-UK 0 85
Share - Bookmark