Consequences of Traumatic Brain Injury for Human Vergence Dynamics

Article English OPEN
Tyler, Christopher W. ; Likova, Lora T. ; Mineff, Kristyo N. ; Elsaid, Anas M. ; Nicholas, Spero C. (2015)
  • Publisher: Frontiers Media S.A.
  • Journal: Frontiers in Neurology, volume 5 (issn: 1664-2295, eissn: 1664-2295)
  • Related identifiers: pmc: PMC4315029, doi: 10.3389/fneur.2014.00282
  • Subject: binocular eye movements | divergence | RE | convergence | Neuroscience | traumatic brain injury | oculomotor dynamics | Original Research | vergence

Purpose: Traumatic brain injury involving loss of consciousness has focal effects in the human brainstem, suggesting that it may have particular consequences for eye movement control. This hypothesis was investigated by measurements of vergence eye movement parameters. \ud \ud Methods: Disparity vergence eye movements were measured for a population of 123 normally sighted individuals, 26 of whom had suffered diffuse traumatic brain injury (dTBI) in the past, while the remainder served as controls. Vergence tracking responses were measured to sinusoidal disparity modulation of a random-dot field. Disparity vergence step responses were characterized in terms of their dynamic parameters separately for the convergence and divergence directions. \ud \ud Results: The control group showed notable differences between convergence and divergence dynamics. The dTBI group showed significantly abnormal vergence behavior on many of the dynamic parameters. \ud \ud Conclusion: The results support the hypothesis that occult injury to the oculomotor control system is a common residual outcome of dTBI.
  • References (17)
    17 references, page 1 of 2

    1. Tyler CW. Binocular eye movements in health and disease. Hum Vis Electron Imaging (2012) 17:8651-34. doi:10.1117/12.2012253

    2. Rashbass C, Westheimer G. Disjunctive eye movements. J Physiol (1961) 159:339-60.

    3. Erkelens CJ, Van Der Steen J, Steinman RM, Collewijn H. Ocular vergence under natural conditions. I. Continuous changes of target distance along the median plane. Proc R Soc Lond B Biol Sci (1989) 236:417-40. doi:10.1098/rspb.1989.0030

    4. Hung GK, Ciuffreda KJ, Semmlow JL, Horng JL. Vergence eye movements under natural viewing conditions. Invest Ophthalmol Vis Sci (1994) 35:3486-92.

    5. Bahill AT, Clark M, Stark L. The main sequence, a tool for studying human eye movements. Math Biosci (1975) 24:191-204. doi:10.1016/0025- 5564(75)90075-9

    6. Tyler CW, Elsaid AM, Likova LT, Gill N, Nicholas SC. Analysis of human vergence dynamics. J Vis (2012) 12(11):21. doi:10.1167/12.11.21

    7. United States Government Accountability Office. VA Healthcare: Mild Traumatic Brain Injury Screening and Evaluation Implemented for OEF/OIF Veterans, but Challenges Remain. Washington, DC: USGAO (2008).

    8. Shenton ME, Hamoda HM, Schneiderman JS, Bouix S, Pasternak O, Rathi Y, et al. A review of magnetic resonance imaging and diffusion tensor imaging findings in mild traumatic brain injury. Brain Imaging Behav (2012) 6:137-92. doi:10.1007/s11682-012-9156-5

    9. Goodrich GL, Kirby J, Cockerham G, Ingalla SP, Lew HL. Visual function in patients of a polytrauma rehabilitation center: a descriptive study. J Rehabil Res Dev (2007) 44:929-36. doi:10.1682/JRRD.2007.01.0003

    10. Ciuffreda KJ, Rutner D, Kapoor N, Suchoff IB, Craig S, Han ME. Vision therapy for oculomotor dysfunctions in acquired brain injury: a retrospective analysis. Optometry (2008) 79:18-22. doi:10.1016/j.optm.2007.10.004

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