Photoplethysmography and electrocardiography for real time evaluation of pulse transit time A diagnostic marker of peripheral vascular diseases

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Terminelli, L. ; Carpignano, F. ; May, J.M. ; Merlo, S. ; Kyriacou, P. A. (2014)

In this work, we report the results of a project, devoted to the development of a real time analysis for non-invasive monitoring of pulse transit time values on people affected by peripheral vascular diseases. Pulse transit time was computed as the time difference between every R-peak of the electrocardiographic signal and the following photopletysmographic peak. Both types of signals were acquired from 12 volunteers and real time signal analysis was performed in LabVIEW. Pathological conditions were simulated on every individual by means of an external cuff pressure applied on their arm. As expected, a PTT increase for increasing values of applied pressure was observed for all the volunteers. The proposed real time analysis could be suggested as a new, non-invasive optical method for real time monitoring of pulse transit time on patients affected by peripheral vascular diseases.
  • References (6)

    [1] J. Allen, “Photoplethysmography and its application in clinical physiological measurement,” Physiol. Meas., vol. 28, pp. R1-R39, 2007.

    [2] R. P. Smith, J. Argod, J. L. Pépin, and P. a Lévy, “Pulse transit time: an appraisal of potential clinical applications”, Thorax, vol. 54, no. 5, pp. 452-7, 1999.

    [3] P.A. Kyriacou et al, “Pilot investigation of photoplethysmographic signals and blood oxygen saturation values during blood pressure cuffinduced hypoperfusion,” Measurement, vol. 42, pp. 1001-1005, 2009.

    M. Hickey et al., “Investigation of photoplethysmography signals and blood oxygen saturation values obtained from human splanchnic organs using a fiber optic sensor,” J. Clin Monit Comput, vol. 25, pp. 245-255, 2011.

    [5] J. Allen, A. Murray, “Age-related changes in peripheral pulse timing characteristics at the ears, fingers and toes,” J. Hum Hypertens, vol. 16, pp. 711-717, 2002.

    [6] D. Zheng, J. Allen, A. Murray, “Effect of External Cuff Pressure on Arterial Compliance”

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