The infectious intestinal disease study of England: a prospective evaluation of symptoms and health care use after an acute episode

Other literature type, Article English OPEN
Cumberland, P ; Sethi, D ; Roderick, PJ ; Wheeler, JG ; Cowden, JM ; Roberts, JA ; Rodrigues, LC ; Hudson, MJ ; Tompkins, DS (2003)

The sequelae of Infectious Intestinal Disease (IID) in a population-based sample of cases and matched controls were investigated for a period of 3 months following the initial infection. Incident cases of IID presenting to GPs or occurring in the community and controls were studied at 3 weeks and over a 3-month follow-up period. Cases were six times more likely than controls to have gastrointestinal symptoms, particularly diarrhoea, at 3 weeks. Ten per cent of cases consulted their GP in the 3 months after episode and 2.3% were referred to hospital. GP presentation rates were twice as high in cases. Gastrointestinal symptoms persist after IID, leading to an increased likelihood of GP consultation and hospital referral. Diagnosis of irritable bowel syndrome may be more likely following IID. The burden of IID is likely to be considerable given its high incidence and the frequency of such sequelae.
  • References (23)
    23 references, page 1 of 3

    1. Wheeler JG, Sethi D, Cowden JM, et al. Study of Infectious Intestinal Disease in England : Rates in the community, presenting to GPs and reported to national surveillance. BMJ 1999 ; 318 : 1046-50.

    2. Statutory Notifications of Infectious Diseases, PHLS, 2002. www.phls.co.uk.

    3. Fleming DM, Ross AM, Chapman RS. Weekly Returns Service Annual Report for 2001, Birmingham : Birmingham Research Unit of the Royal College of General Practitioners, 2001.

    4. Neal KR, Hebden J, Spiller R. Prevalence of gastrointestinal symptoms six months after bacterial gastroenteritis and risk factors for development of the irritable bowel syndrome : postal survey of patients. BMJ 1997 ; 314 : 779-82.

    5. Keat A. Infections and the immunopathogenesis of seronegative spondyloathropathies. Current Opin Rheumatol 1992 ; 4 : 494-9.

    6. Moake JL. Haemolytic uraemic syndrome - basic science. Lancet 1994 ; ii : 393-7.

    7. McCarthy N, Giesecke J. Incidence of Guillain-Barre Syndrome following infection with Compylobacter jejuni. Am J Epidemiol 2001 ; 153 : 610-4.

    8. Infectious Intestinal Disease Study Executive Committee. A Report of the Study of Infectious Intestinal Disease in England. London : HMSO, 2000.

    9. Sethi D, Wheeler JG, Cowden JM, et al. A study of infectious intestinal disease in England : plan and methods of data collection. Commun Dis Public Health 1999 ; 2 : 101-7.

    10. Department of Health. New clinical classification system will streamline computerised medical records. London : Department of Health, 1990.

  • Metrics
    No metrics available
Share - Bookmark