Lifting the differentiation embargo

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Latif, Anne-Louise; Holyoake, Tessa;
  • Publisher: Elsevier (Cell Press)
  • Subject:
    mesheuropmc: hemic and lymphatic diseases

Effective differentiation therapy for acute myeloid leukemia (AML) has been restricted to a small subset of patients with one defined genetic abnormality. Using an unbiased small molecule screen, Sykes et al. now identify a mechanism of de-repression of differentiation ... View more
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